ID NUMBER: 813002622
COUSE CODE: BIOL 2360
SUPPLEMENTS-EXTRA CREDIT ASSIGNMENT
Does anyone really think that the claims made by Brock Beauty about hairfinity are true?
Manufacturers claim that hairfinity accomplishes the following:
- Nourishes hair from the inside out,
- Stimulates faster growing hair,
- Produces longer, thicker, stronger and more vibrant hair.
A list of the active ingredients in hairfinity includes:
- Niacin (Vitamin B3)
- Vitamin A
- Vitamin C
- Vitamin D
- Vitamin B12
- Vitamin B Complex
- EXCLUSIVE CAPILSANATM COMPLEX
What in the world am I putting in me? I thought you would have asked that question. Here is an explanation based on biochemistry!
JUSTIFICATION OF MANUFACTURER’S CLAIM;
Figure 1: Structure of Biotin
Biotin is a water-soluble form of the vitamin B group which is responsible for the metabolism of proteins, fats and carbohydrates to release energy. Biotin reacts with cellular enzymes by behaving as a prosthetic group (coenzyme) for carboxylase enzymes. Activation of the carboxylase enzymes occur as a result of the covalent binding of biotin to the epsilon-amino group of lysine residues of the inactive apo-carboxylases via ATP-dependent holo-carboxylase synthetase. The products of such reactions are active holo-carboxylase and ADP and inorganic phosphates. This reaction is as follows:
apo-carboxylases + biotin →→→→→→→ holo-carboxylases
(Inactive) ↑ ↓ (Active) ATP ADP +Pi Finally, biotinyl moiety from the epsilon-amino residues are cleaved by biotinidase which produces free, re-usable biotin. Now the holocarboxylase enzymes catalyse reactions in amino acid synthesis, gluconeogenesis and fatty acid synthesis with amino acids, glucose and fatty acids products respectively. The holocarboxylases cause the production of amino acids, which join together by peptide bonds via condensation reactions to make dipeptides.
Figure 2: Condensation reaction showing peptide formation
A series of condensation reactions produce polypeptides. Further lengthening and coiling of these polypeptides produces proteins. One major component of hair is protein. The type of protein found in hair is called keratin. Keratin can therefore be made by biotin. This means that biotin ultimately promotes faster hair growth as an increased intake of biotin in the cell subsequently entails a higher percentage of amino acid production which directly correlates to more protein (keratin) production. Also, the claim that hairfinity nourishes the hair from inside out and produces thicker, stronger and more vibrant hair is also deemed true as biotin affects cellular reactions which produce the keratin in your hair.
Figure 3: Biotin reaction scheme
The claims made by hairfinity’s manufacturers align with the biochemical explanations with respect to biotin. Biotin contributes to hair nourishment and the production of stronger, thicker, more vibrant looking hair as well as the promotion of faster hair growth. This product contains more active ingredients but due to the restrictions of this assignment, only biotin was highlighted. Thank You! Hope you had a good read! ;). Hairfinity…
Asale, Eshe. 2011. “Vitamins That Double Hair Growth.” http://www.livestrong.com/article/213387-vitamins-that-double-hair-growth/ Accessed November 24, 2014.
Hairfinity. 2014. “Hairfinity”. http://www.hairfinity.com/ingredients.htm. Accessed November 24, 2014.
HairNeedCare. 2014. “Sebum in hair-How to control, what happens When Overproduced.” http://www.hairneedcare.com/how-to-control-sebum-in-hair.html Accessed November 24, 2014.
Nall, Rachel. 2013. “How Does Biotin Make Your Hair Grow faster?” http://www.livestrong.com/article/69844-biotin-make-hair-grow-faster/ Accessed November 24, 2014.
PubMed.gov. 2000. “[Importance of biotin metabolism].” http://www.ncbi.nlm.nih.gov/pubmed/10846444 Accessed November 24, 2014.
Scheinfeld, S Noah, MD, JD, FAAD. S B Freilich, MD, M R Mascarenhas, MBBS, M L Windle, PharmD, M P M Poth, MD Jatinder Bhatia, MBBS.http://emedicine.medscape.com/article/984803-overview#a0104 Accessed November 24, 2014.